Inheritance plays a big part in 12 cancers: Study


Subodh Varma


Scientists have found strong evidence for inherited components in 12 different kinds of deadly cancers. This raises hope for earlier detection and better targeting of therapy. While the new study confirms the role of inherited genes in breast and ovarian cancer, the surprising discovery was that even stomach cancer has an evident link with genes passed down from parents.
Other types of cancer analysed in the study included those found in prostate, lungs, brain and nervous system, uterus, blood, etc.

“In general, we have known that ovarian and breast cancers have a significant inherited component, and others, such as acute myeloid leukemia and lung cancer, have a much smaller inherited genetic contribution,” said senior author Li Ding of the McDonnell Genome Institute at Washington University. “But this is the first time on a large scale that we’ve been able to pinpoint gene culprits or even the actual mutations responsible for cancer susceptibility.”

The study was carried out by researchers from several US universities including Washington University, St.Louis, Ohio State University, Brown University and Medical College Wisconsin. It was recently published in the scientific journal Nature Communications.


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )


Connecting to %s